On win32: 30gb of "MsgWaitForMultipleObjects() failed: The handle is invalid"

[Charles Duffy]

Gnucash 2.2.1 (r16462) has been working well on win32 for me for a 
significant while -- and then the trace file from a session I left open 
overnight ate the 30GB of free space left on my hard drive.

*   WARN <qof.engine> [guid_init()] only got 2129 bytes.
The identifiers might not be very random.
*   CRIT <gnc.app-util> gnc_detach_process: assertion `proc && 
proc->pid' failed
*   WARN <GLib> gmain.c:436: MsgWaitForMultipleObjects() failed: The 
handle is invalid.
*   WARN <GLib> gmain.c:436: MsgWaitForMultipleObjects() failed: The 
handle is invalid.
*   WARN <GLib> gmain.c:436: MsgWaitForMultipleObjects() failed: The 
handle is invalid.
*   WARN <GLib> gmain.c:436: MsgWaitForMultipleObjects() failed: The 
handle is invalid.
*   WARN <GLib> gmain.c:436: MsgWaitForMultipleObjects() failed: The 
handle is invalid.
*   WARN <GLib> gmain.c:436: MsgWaitForMultipleObjects() failed: The 
handle is invalid.
*   WARN <GLib> gmain.c:436: MsgWaitForMultipleObjects() failed: The 
handle is invalid.

...followed by very, very, very much of the same.

This issue is not, unfortunately, reliably reproducible.