locked database

[drakeBiosci]

I've been using gnucash (GNOME) for about 6 mos -- no problems til now.
Recently updated to Gutsy and Gnucash 2.2.1, and turned on the autosave
feature. Now when I run gnucash I get the following error

GnuCash could not obtain the lock for /home/username/filename

Moving on, if I say "open anyway" the file loads for just a moment then
crashes, Tried different suggestions from this forum (delete .lck files,
opening with --nofile and turning off scheduled transaction) but no luck.

Running from terminal I get 

gnc.bin-Message: main: binreloc relocation support was disabled at configure
time.

and then when it crashes 

Found Finance::Quote version 1.13
Backtrace:
In current input:
   1: 0* (let ((options #)) (let (#) (# option)) (let (#) (# option)) ...)
   1: 1* (let ((option #)) ((lambda # #) option))
   2: 2  [#<procedure #f (option)> #("General" "Budget" "a" ...)]
   ...
   2: 3  [#<procedure #f args> #f]
In /usr/share/gnucash/scm/options.scm:
  88: 4* [apply #<procedure #f (x)> (#f)]
In unknown file:
   ?: 5  [#<procedure #f (x)> #f]
In /usr/share/gnucash/scm/options.scm:
 341: 6* (set! value (budget->guid x))
 341: 7* [budget->guid #f]
 315: 8  (if (string? budget) budget (gncBudgetGetGUID budget))
 317: 9  [gncBudgetGetGUID #f]

But this means nothing to me. Any advice? Much thanks.
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